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There’s plenty of local GAA action on around the county this weekend.First up this afternoon is the meeting of near neighbours Arravele Rovers and Galtee Rovers in the West Senior Football Final.Both have to win west to stay in the county, however Galtee Rovers have the upper hand, having beaten Arravale in the recent O’Donoghue Cup final. Photo ©Stephen Gleeson The game throws in in Annacarthy at 3 o’clock, and Arravale Selector Tommy Twoomey says they’ll have to be ready for the Galtee’s challenge…Before that game, at 1.30, Rockwell Rovers meet Clonoulty Rossmore in the intermediate decider.Then this evening at half 5, Killenaule meet Carrick Swans in the South Senior Hurling Final.Swans are the most decorated south tipp hurling club with 22 south titles to their name.However, Killenaule have 21 titles, and a win this evening would see them level with Swans.That game is on in Fethard.Also down for decision this evening is the North Senior hurling final which throws in at 6pm in NenaghNenagh Eire Og face Borrisoleigh, in what is expected to be a pulsating game.Borrisoleigh Coach Johnny Kelly is a Portumna man, and with the Galway in the All Ireland Final tomorrow, he says his sole focus is on the North game…Finally this evening sees the Mid Tipp Intermediate hurling final at 6 o clock in Holycross.It sees Thurles Sarsfields up against Gortnahoe Glengoole.
Manchester United fought back to defeat Braga and reach the last 16 of the Champions League as Group H winners.Alan put Braga ahead early in the second half with a powerful penalty.A power cut just before the hour resulted in floodlight failure, before play resumed after a 12-minute delay.Substitute Robin van Persie then fired over a stranded Beto before Wayne Rooney despatched a penalty into the top corner and Javier Hernandez stabbed in a stoppage-time third.The win in Portugal, United’s fourth in as many European games, means they top the group with 12 points, eight ahead of Galatasaray with two games remaining. That is in stark contrast to their performance in the Champions League last season, when they failed to progress beyond the group stage for only the third time in 17 years. Just as he did in the reverse fixture at Old Trafford last month, Sir Alex Ferguson opted to reshuffle his defence, giving Chris Smalling his first start since suffering a metatarsal injury in pre-season alongside Jonny Evans at centre-back.United went 2-0 down before fighting back to win 3-2 last time, and once again Braga immediately looked to find gaps in the visitors’ backline.First, Eder took advantage of Evans’s hesitancy to nip in and flash the ball across the face of goal but, fortunately for United, no Braga player was waiting in the box, before Ruben Micael sent a long-range effort just wide after he was afforded space outside the area.Braga were denied by the woodwork in the 22nd minute as Hugo Viana delivered a cross into the area that Eder dived to meet, but the Portugal international could only watch on as his header bounced back off the post.United, meanwhile, were seemingly in no rush to search for an opening, and their only effort of note in a forgettable first half was Evans’s harmless looping header from Antonio Valencia’s cross, which was easily collected by Braga keeper Beto. The visitors’ hopes of confirming their place in the last 16 was dealt a blow when they fell behind four minutes into the second half.Custodio’s run into the box was stopped by Evans and referee Felix Brych pointed to the penalty spot. Alan stepped up to confidently put the ball high into the net for his third goal against United in this year’s competition.United attempted to respond three minutes later as Nani’s shot was deflected wide, before Danny Welbeck was adjudged to have handled the ball inside the area, with the striker in a promising position. Despite those half-chances, United were still looking distinctly off key and were given a chance to regroup just before the hour when suddenly half of the stadium was plunged into darkness due to floodlight failure.The players returned to their respective dressing rooms as the problem was looked into, giving Ferguson an impromptu chance for a team talk, before power was restored and play was able to continue. United re-emerged with Rio Ferdinand taking the place of Evans as Ferguson looked to improve his side’s defending, before Van Persie was also introduced in the 64th minute and it was the Dutch international who levelled matters 10 minutes from time.Anderson sent a long free-kick for Van Persie to chase and the striker spotted Beto inexplicably racing off his line. He took full advantage, curling an effort above the Braga keeper’s grasp and into the net.A point was all United needed to progress, but they took the lead in the 85th minute when Rooney was brought down inside the box by Nuno Coelho and, after a brief delay, the referee pointed to the spot, with Rooney picking himself up to smash the ball into the top corner.There was just time for Ferguson’s side to put a gloss on the scoreline when Rooney fed a pass across the area to Hernandez, who rounded Beto before stabbing the ball through the legs of a defender on the line and into the net.
An idea that has come up and been rejected from time to time regarding Florida’s capital is back again.Democratic Senator Kevin Rader, of Delray Beach, wants lawmakers to consider moving our state capital from Tallahassee.He filed the proposal (SB 112) for consideration during the 2020 legislative session, which starts this January.The proposal requests that the Legislature’s Office of Program Policy Analysis and Government Accountability study the cost of relocating the flagship city to Central Florida, and the related economic impact to Tallahassee and its surrounding area.Rader, who seeks to have the study completed by the end of 2021, wants the analysis to include information about travel costs to the state capital.On a similar note, former Republican Representative Bill Hager, of Delray Beach, also proposed a measure last year to form a task force to examine options for relocating the Capitol building, executive-branch offices and Legislature. It failed to get heard in committees.Tallahassee was selected as the state’s territorial capital in 1824, since it was located midway between Florida’s two principal cities – St. Augustine and Pensacola, according to the Florida Department of State.Voters rejected a referendum in 1900 to relocate the capital. In 1969, a debate on relocation also surfaced, but never made it to the ballot.In 1972, the state Legislature agreed to build the 22-story Capitol building that stands behind the Old Capitol.
Laymen appreciate scientists who can express complex concepts in everyday terms. Here’s a good example from the Wistar Institute:Around the home, regularly used tools are generally kept close at hand: a can opener in a kitchen drawer, a broom in the hall closet. Less frequently used tools are more likely to be stored in less accessible locations, out of immediate reach, perhaps in the basement or garage. And hazardous tools might even be kept under lock and key. Similarly, the human genome has developed a set of sophisticated mechanisms for keeping selected genes readily available for use while other genes are kept securely stored away for long periods of time, sometimes forever. Candidate genes for such long-term storage include those required only for early development and proliferation, potentially dangerous genes that could well trigger cancers and other disorders should they be reactivated later in life.The article discusses how researchers at Wistar Institute found a two-molecule complex that governs how the chromatin that packages DNA will become either loosely organized or tightly condensed. Some unknown switching mechanism determines how ASF1 will bind to one of two similar molecules, HIRA and CAF1, that determine the degree of tight packing:An unanticipated observation from the study centers on the region of association between the two molecules in the complex. The researchers knew that one of the two molecules in the complex, called ASF1, associated with a particular molecular partner, HIRA, when directing assembly of the more condensed form of chromatin. But it could also associate with a different partner, called CAF1, to shepherd assembly of the less condensed form of chromatin. On closer study, the scientists discovered that HIRA and CAF1 have nearly identical structural motifs in the regions of interaction with ASF1. This means that ASF1 can bind to one or the other molecular partner, but not to both. In other words, the interaction is mutually exclusive: A kind of decision is made by ASF1 as to whether to guide the assembly process towards the more or less condensed forms of chromatin. What determines the choice? The relevant factors are unknown for now.However it works, it’s important: one researcher explained, “Appropriate packaging of the DNA in the cell nucleus is crucial for proper functioning of the cell and suppression of disease states, such as cancer.” The research has been published online in Nature Structural and Molecular Biology.11Tang et al., “Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly,” Nature Structural and Molecular Biology, Oct. 2006, published online: 17 September 2006; doi:10.1038/nsmb1147.Good work, by scientists operating on design principles (whether they realize it or not). There was no mention of evolution in the press release. It would would seem, also, that evolutionary theory would be useless in tracking down the factors that determine which binding takes place. You might not have realized that your genetic toolkit has power tools that are dangerous. Just like you would lock up hunting rifles in a secure cabinet, so that they won’t be used for the wrong purpose, your genetic system has controlled procedures for locking up its dangerous equipment. Most of the trillions of cells in your body get it right for decades, and even when there’s an accident, the body has other procedures for containing the damage. It is mind-boggling that all this goes on without our conscious knowledge, so that we can be conscious, and gain knowledge.(Visited 7 times, 1 visits today)FacebookTwitterPinterestSave分享0
The 5D was always for photographers. The Canon 5D Mark IV makes it official.All images and videos via Canon It’s finally here. The Canon 5D Mark IV has officially been announced and is available for pre-order. Photographers will be pretty happy, and videographers will continue to wonder what camera to get next.With an MSRP of $3499, the camera will still be a great option for photographers. The stills are great, and the upgrades from the Mark III are plentiful. Seeing that this is a community and blog focused on videographers, let’s talk about the video capabilities.We were pretty excited about the long overdue update, as detailed in the several camera rumor posts written this year. Yet with every new rumor, our interest waned. Now that the Canon 5D Mark IV is here, I know I’m personally full of disappointment. This camera’s video capabilities are the epitome of — MEH. Remember back in school when you really wanted that awesome new toy, and you annoyed your parents until they caved? Then when you got it, you played with it for a whopping two minutes before it broke or bored you? That is the Canon 5D Mark IV for me. Videographers clamored for 4K footage for years from a Canon DSLR, the 5D Mark IV delivers by shooting 4K video up to 30fps.This is credited as “the first full-frame Canon DSLR to shoot high-quality slow motion” if you need 120fps in 720p. Let’s be honest, this isn’t a slow-motion video camera. In fact, the Canon 5D Mark IV isn’t a video camera at all. It never was, and now we know it never will be. This DSLR was always built for photographers, and Canon just happened to luck into the video industry. If you want a Canon video camera, that’s why the Cinema EOS series exists.Canon released a whole series of videos for the launch of the 5D Mark IV. The video that got all the attention (and probably budget) promotes the camera’s photography specs and new internal updates. Take a look here.As far as videos promoting the video capabilities, the videos are lackluster at best. In fact, I can’t believe that most of these are officially released videos. Here is a short 3:20 clip (even though it feels much longer) showing off the 5D Mark IV at the beach.We know the photos will look great, so timelapse videos should look stellar. Why they released a demo timelapse video of a person building a wooden ship in a controlled studio environment that is in need of more light, I have no idea.I guess for those wanting to use the 5D Mark IV’s wifi capabilities with their phones to instantly post to social media, Canon released this vertical demo of slow-motion footage. It’s a very odd approach, as the footage doesn’t look much better had it been shot on the phone itself.These have to be the most bizarre product release videos I’ve ever seen from a major manufacturer. The only decent promo for the cameras video specs came from Bruce Dorn, who demonstrates shooting 4K and pulling stills from 4K footage.In the end, this camera will still make a ton of money, but I’m fairly certain that this iteration of the 5D will officially make videographers jump ship to the likes of Sony a Series or Panasonic Lumix G series.If you had any doubt on the camera’s intended audience, this should clear things up. This image is on the Canon Australia homepage. Actual Australian Ad via CanonFor photographers interested in specs, and videographers looking for something to complain about, here are all the camera details.Specs:Canon EF Mount30.4MP Full-Frame CMOS SensorDIGIC 6+ Image Processor3.2″ 1.62m-Dot Touchscreen LCD MonitorDCI 4K Video at 30 fps; 8.8MP Still Grab1080p up to 60fps720p up to 120fps61-Point High Density Reticular AFNative ISO 32000, Expanded to ISO 102400Dual Pixel RAW; AF Area Select ButtonDual Pixel CMOS AF and Movie Servo AF7 fps Shooting; CF & SD Card SlotsBuilt-In GPS and Wi-Fi with NFCWhat are your thoughts on the Canon 5D Mark IV? Share your opinions in the comment section below.
Fresh snowfall only added to the prevailing deafening and eerie silence at Kulgam’s Batagund village, home to 38-year-old Nazir Ahmad Wani, the Kashmir valley’s first ever awardee of the Ashok Chakra — India’s highest peacetime military decoration. Ironically, the district also became a hotbed of militancy last year.Also Read Kashmir’s first Ashok Chakra for Lance Naik Nazir Ahmad Wani Lance Naik Wani’s posthumous military decoration is least talked about in militancy-affected Kulgam, which saw 26 civilian deaths either near encounter sites or in street protests. At least 15 local militants were killed in more than 50 major operations conducted in the district.At the spare three-storey house of the Wanis, younger brother Mushtaq Ahmad is reticent and all guests are not welcome. “A few days ago, locals knocked on our door and broke the news about the award. The fact of the day is we lost him,” said the younger Wani, referring to his brother.Curious locals are keeping a tab on all guests visiting the house.“Kulgam has suffered the most in 2018,” said Majid Ganai, a local resident. “It was a year of funerals. We saw militants, informers, soldiers and policemen, all locals, returning home draped in coffins. Funerals were also only occasions of celebrations. Wani’s feat could hardly be discussed in these times,” he added.The Wanis’ neighbours said Wani had been shooed away by militant commander Mohammad Ayoub from nearby Bhan village, who had rejected his offer to join militancy. In 1992, Wani joined the Ikhwan, a local name for an irregular counter-insurgency force drawn from locals. Married to his school-time sweetheart Mahajabeen in 2002, Wani’s two children, Athar, a Class 10 student, and Shahid, a Class 8 student, would shuttle between Jammu and the Valley “to ensure their safety”. Wani would always drop by uninformed at home, as the militants stepped up attacks on local soldiers, killing at least three members of the armed forces in their houses.Regularised in the Army in 2004, his counter-insurgent colleague Mukhtar Ahmad Malik alias Mukhtar Gola’s killing saw Wani pledging to go after the killers. In September, Lashkar-e-Taiba (LeT) militants shot Malik dead inside his house in Shurat village. The killing was filmed on a mobile phone by the militants, who fired from inside the pheran, a long woolen robe.One-and-half months later, Wani volunteered to take on the LeT’s Umar Ganai and his five associates, the main suspect behind Malik’s killing, on November 25 in Hirapur village in Shopian. Ganai and Wani shot each other dead in the encounter, said a police officer, declining to be identified.The citation for the award, issued by the Rashtrapati Bhawan, reads: “Lance Naik Wani epitomised qualities of a fine soldier. He always volunteered for challenging missions, displaying great courage under adverse circumstances, exposing himself to grave danger in the line of duty.”Meanwhile, Governor Satya Pal Malik said Wani would always be an inspiration for the generations to come and motivate them to work selflessly for the safety and security of the country.
A ring isn’t the only thing Urban Meyer will be getting as a result of Ohio State’s national championship. The Buckeyes’ coach will also be getting a tattoo. Prior to his team’s game against Oregon in the inaugural College Football Playoff National Championship Game, Meyer promised his players he would get inked up if they beat the Ducks. They did, 42-20, so the 50-year-old will be visiting a tattoo parlor at some point in the near future. Friday evening, Meyer made an appearance on the Late Show With David Letterman. He talked about the tattoo he’ll be getting at about the 1:05 mark. While a Block O on top of his head seems like an interesting idea, odds are Meyer will probably opt to get something on his chest or back like Rick Pitino.
Events recently took place across the UK to mark the 70th anniversary of the founding of the NHS – Britain’s National Health Service.Prince of Wales Celebrates 70th Anniversary of NHSMembers of the Royal Family met NHS staff and patients in England, Scotland and Wales.The Prince of Wales – already in Wales for his annual week of engagements to celebrate Welsh achievement and culture – started the day with a Garden Party at Ysbyty Aneurin Bevan hospital. Aneurin Bevan – the Welsh son of a coal miner and founder of the NHS – is a source of much pride in Wales.In the afternoon, The Countess of Wessex attended a service at Westminster Abbey where a number of the NHS’s longest-serving members of staff were amongst the congregation.At the final Royal event of the day, The Duke of Cambridge spoke to NHS staff and patients about their experience within the health service during a reception in Scotland.Source:Royal.uk
OTTAWA – The federal Liberals will ask a group of advisers, led by Ontario’s former health minister, to explore options for a national program to cover the cost of prescription drugs and report back in 2019 — ensuring pharmacare becomes a key election campaign issue.The measure forms a part of a trinity of major drug initiatives in Tuesday’s federal budget, the other two being a $231-million package of steps that aims to confront Canada’s escalating opioid crisis, including $150 million in emergency funding, and tax changes for cannabis-based pharmaceuticals.Former Ontario health minister Eric Hoskins will head up an advisory council to come up with options on how to create a national pharmacare program — a program that the parliamentary budget watchdog has warned could cost $19 billion a year.The work will include consulting with provinces, territories and Indigenous groups about what drugs should be included, and the costs involved for “whatever model that we choose,” Health Minister Ginette Petitpas Taylor said after the budget speech with Hoskins at her side.Hoskins won’t have to deliver a final report until the spring of 2019, setting the stage for the Liberals to make pharmacare a centrepiece of the party’s election campaign and take a key talking point away from NDP Leader Jagmeet Singh.Following Finance Minister Bill Morneau’s speech, Singh seemed unfazed by the prospect, noting that the Liberals were only promising to examine the issue. He even dared the government to steal his party’s proposal and implement a national pharmacare plan.“What the government is proposing is not a plan. This is a fantasy,” Singh said. “We want to introduce a program now.”Conservative Leader Andrew Scheer said “Canadians should brace themselves” about what might come, because a former Ontario Liberal cabinet minister shouldn’t be trusted to craft “any kind of plan, never mind one in the health care field.”The Liberals say they won’t apply a new excise tax to cannabis-based pharmaceutical products that can be obtained with a prescription once marijuana is legalized this year.Nor will the excise tax be applied to oils that contain low amounts of THC, the primary psychoactive element in marijuana, that are used by children with certain medical conditions.The government wants to tax legal marijuana at either $1 per gram or one-tenth of a product’s price, whichever is greater.But those medications represent a minority of those used by patients, according to one group. Canadians for Access to Medical Marijuana also questioned the wording behind a budget promise to consider retroactively reimbursing patients an unspecified amount for taxes already paid on cannabis-based pharmaceuticals.“Exempting a small minority of patients does not address the affordability issue and implies some patients are more legitimate than others. Looking into a reimbursement program implies patients can afford to pay for their medicine in the first instance. They can’t,” director Jonathan Zaid said in a statement.The Opposition Conservatives have chided the government for moving too fast on legal pot, suggesting there are outstanding public safety issues that need to be addressed.The budget outlines $62.5 million over five years beginning this year for public education programs around cannabis use, and a further $20 million over five years for research by the Mental Health Commission of Canada and the Canadian Centre on Substance Use and Addiction.The Liberals are also spending $80.5 million over five years starting this year to reduce tobacco use, particularly in Indigenous communities, and raising taxes on cigarettes by $1 per carton.On opioids, provinces and territories will receive $150 million in emergency funding this year to deal with a crisis that is projected to claim more than 4,000 lives this year.The balance of the $231.4 million will go towards public education campaigns, better access to public health data and new equipment and tools to allow border agents to better detect dangerous opioids like fentanyl before they enter the country.— With files from Geordon Omand and Lee BerthiaumeNote to readers: This is a corrected story. An earlier version carried a headline suggesting the government already taxes cannabis-based pharmaceuticals, and did not reflect that certain cannabis-based pharmaceuticals will be exempt from new excise taxes.